HSD17B13-IN-29 - CAS 2770246-48-3

Compound 53, also known as HSD17B13-IN-29, is an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 ≤ 0.1 μM for estradiol. This compound is applicable in the study of liver, metabolic, and cardiovascular diseases, including NAFLD and NASH, and for investigating drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770246-48-3

C23H14Cl2N4O3

465.29

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(C#N)C=CC=C4)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound