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HSD17B13-IN-33 - CAS 2730027-85-5
HSD17B13-IN-33 - CAS 2730027-85-5
SKU:MF-0120734-01
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Product Details
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Bioactivity
HSD17B13-IN-33 (Compound 115), a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits an IC 50 of less than 0.1 μM for estradiol. This compound is applicable in the research of liver diseases, metabolic disorders, and cardiovascular conditions including NAFLD, NASH, and drug-induced liver injury (DILI) [1].
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Target
Dehydrogenase
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Related Pathways
Metabolism
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CAS Number
2730027-85-5
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Molecular Formula
C20H17F2N3O3
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Molecular Weight
385.36
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SMILES
FC1=CC=C(OC2=NC(=NC=C2)C=3C=CC(=CC3)N4CCOCC4)C(F)=C1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound