HSD17B13-IN-35 - CAS 2770246-69-8

HSD17B13-IN-35 (compound 76) is a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 μM using estradiol as the substrate. This compound is significantly relevant in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

Dehydrogenase

Metabolism

2770246-69-8

C25H16Cl2FN5O3

524.33

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=NN(C=C4)C5=C(F)C=CC=C5)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound