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HSD17B13-IN-36 - CAS 2730027-86-6
HSD17B13-IN-36 - CAS 2730027-86-6
SKU:MF-0147646-01
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$1,383.80 USD
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Product Details
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Bioactivity
HSD17B13-IN-36 (compound 116) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of <0.1 μM with estradiol as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including NASH (nonalcoholic steatohepatitis) [1].
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Target
Dehydrogenase
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Related Pathways
Metabolism
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CAS Number
2730027-86-6
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Molecular Formula
C20H17F2N3O4S
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Molecular Weight
433.43
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SMILES
O(C1=NC(=NC=C1)C2=CC=C(C=C2)N3CCS(=O)(=O)CC3)C4=C(F)C(O)=C(F)C=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound