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HSD17B13-IN-48 - CAS 2770246-12-1

HSD17B13-IN-48 - CAS 2770246-12-1

MF-0120745-01

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Product Details

  • Bioactivity

    HSD17B13-IN-48 (Compound 12) serves as an inhibitor for hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the study of liver, metabolic, and cardiovascular diseases, including NAFLD, NASH, and drug-induced liver injury (DILI) [1].

  • Target

    Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    2770246-12-1

  • Molecular Formula

    C23H16Cl2FN3O3

  • Molecular Weight

    472.3

  • SMILES

    N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN([C@@H](C)C4=CC(F)=CC=C4)C3=O)=CC=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound