HSD17B13-IN-49 - CAS 2770246-74-5

HSD17B13-IN-49 (Compound 81) acts as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 0.1 μM for estradiol. It is utilized in studies exploring liver, metabolic, and cardiovascular diseases, including NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770246-74-5

C23H13Cl3F3N3O4

558.72

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(Cl)C=C2

-20°C

Ice Packs

Small Compound