HSD17B13-IN-51 - CAS 2770246-75-6

HSD17B13-IN-51 (Compound 82), an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits potent activity with an IC50 value of ≤ 0.1 μM against estradiol. This compound is useful in researching various conditions including liver, metabolic, and cardiovascular diseases—specifically NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770246-75-6

C22H13Cl2F3N4O3

509.26

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(C(F)(F)F)N=CC=C4)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound