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Molfinity

HSD17B13-IN-52 - CAS 2770246-77-8

HSD17B13-IN-52 - CAS 2770246-77-8

SKU:MF-0120748-01

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  • Bioactivity

    HSD17B13-IN-52 (Compound 84), an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits potent activity with an IC50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the research of various health conditions including liver, metabolic, and cardiovascular diseases, specifically NAFLD, NASH, and drug-induced liver injury (DILI) [1].

  • Target

    Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    2770246-77-8

  • Molecular Formula

    C26H22Cl2N4O4

  • Molecular Weight

    525.38

  • SMILES

    N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(C=CC=C4)N5CCOCC5)C3=O)=CC=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound