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HSD17B13-IN-52 - CAS 2770246-77-8
HSD17B13-IN-52 - CAS 2770246-77-8
SKU:MF-0120748-01
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Product Details
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Bioactivity
HSD17B13-IN-52 (Compound 84), an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits potent activity with an IC50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the research of various health conditions including liver, metabolic, and cardiovascular diseases, specifically NAFLD, NASH, and drug-induced liver injury (DILI) [1].
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Target
Dehydrogenase
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Related Pathways
Metabolism
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CAS Number
2770246-77-8
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Molecular Formula
C26H22Cl2N4O4
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Molecular Weight
525.38
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SMILES
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(C=CC=C4)N5CCOCC5)C3=O)=CC=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound