HSD17B13-IN-53 - CAS 2770246-81-4

HSD17B13-IN-53 (Compound 88) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 of ≤ 0.1 μM against estradiol. This compound is utilized in the study of liver, metabolic, and cardiovascular diseases, including NAFLD and NASH, besides its application in drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770246-81-4

C24H16Cl2F3N3O4

538.3

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(C)C=C2

-20°C

Ice Packs

Small Compound