HSD17B13-IN-54 - CAS 2770247-49-7

HSD17B13-IN-54 (Compound 158) functions as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 value of ≤ 0.1 μM against estradiol. This compound holds potential for applications in the study of various liver, metabolic, and cardiovascular diseases, including NAFLD and NASH, as well as drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-49-7

C24H15Cl2F4N3O3

540.29

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(C(F)(F)F)C=CC=C4)C3=O)=C(F)C=C2

-20°C

Ice Packs

Small Compound