HSD17B13-IN-55 - CAS 2770247-58-8

HSD17B13-IN-55 (Compound 167) serves as an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 value of ≤ 0.1 μM against estradiol. This compound is particularly useful in research related to liver, metabolic, and cardiovascular diseases including NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-58-8

C25H16Cl2F5N3O3

572.31

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C(F)F)N(CC4=C(C(F)(F)F)C=CC=C4)C3=O)=C(C)C=C2

-20°C

Ice Packs

Small Compound