HSD17B13-IN-57 - CAS 2770246-86-9

HSD17B13-IN-57 (Compound 93) acts as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various health conditions, including liver, metabolic, and cardiovascular diseases—specifically NAFLD, NASH—and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770246-86-9

C24H16Cl2F3N3O5

554.3

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N(C)C(=O)N(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound