HSD17B13-IN-59 - CAS 2770247-11-3

HSD17B13-IN-59 (Compound 177), a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits an IC 50 value of ≤ 0.1 μM for estradiol. This compound is applicable in research related to liver, metabolic, and cardiovascular diseases, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-11-3

C24H17Cl2N5O3

494.33

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC=4C=5C(N(C)N4)=CC=CC5)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound