HSD17B13-IN-60 - CAS 2770247-20-4

HSD17B13-IN-60 (Compound 126) serves as an effective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 value of ≤ 0.1 μM against estradiol. This compound has potential applications in the study of liver, metabolic, and cardiovascular diseases, including nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-20-4

C20H16Cl2FN3O3S

468.33

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C(C(N[C@@H](C)C3=C(F)C=CC=C3)=O)C(C)=NS2

-20°C

Ice Packs

Small Compound