HSD17B13-IN-64 - CAS 2770247-34-0

HSD17B13-IN-64 (Compound 143), an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits a potent IC50 value of ≤ 0.1 μM against estradiol. This compound has applications in the study of various diseases, including liver conditions like NAFLD and NASH, metabolic and cardiovascular disorders, as well as drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-34-0

C21H13Cl3N4O3

475.71

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(Cl)C=CC=N4)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound