HSD17B13-IN-65 - CAS 2770247-59-9

HSD17B13-IN-65 (Compound 168) acts as an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating potent activity with an IC50 value of ≤ 0.1 μM for estradiol. It is applicable in the study of various diseases, including liver, metabolic, and cardiovascular conditions like NAFLD or NASH, and in investigations of drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-59-9

C24H15Cl2F4N3O4

556.29

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=C(F)C=C2

-20°C

Ice Packs

Small Compound