HSD17B13-IN-69 - CAS 2770246-16-5

HSD17B13-IN-69 (Compound 11) functions as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating potent activity with an IC 50 value of ≤ 0.1 μM against estradiol. This compound has practical applications in studying a variety of conditions including liver, metabolic, and cardiovascular diseases, specifically NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770246-16-5

C21H14Cl2N4O3

441.27

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC=4C=CN=CC4)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound