HSD17B13-IN-75 - CAS 2770246-20-1

HSD17B13-IN-75 (Compound 21) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 value of ≤ 0.1 μM for estradiol. Its applications are primarily in the research fields addressing liver diseases, metabolic disorders, and cardiovascular conditions, including NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770246-20-1

C24H16Cl2FN3O3

484.31

O=C1N(C2(CC2)C3=C(F)C=CC=C3)C=NC=4C1=C(NC(=O)C5=CC(Cl)=C(O)C(Cl)=C5)C=CC4

-20°C

Ice Packs

Small Compound