HSD17B13-IN-80 - CAS 2770247-42-0

HSD17B13-IN-80 (Compound 151) serves as an inhibitor for hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating potent activity with an IC 50 ≤ 0.1 μM against estradiol. It is primarily utilized in the investigation of liver, metabolic, and cardiovascular diseases including NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-42-0

C25H18Cl2F3N3O3

536.33

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(C(F)(F)F)C=CC=C4)C3=O)=C(C)C=C2

-20°C

Ice Packs

Small Compound