HSD17B13-IN-81 - CAS 2770247-45-3

HSD17B13-IN-81 (Compound 154) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting potent activity with an IC 50 of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various health conditions, including liver, metabolic, and cardiovascular diseases, particularly non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-45-3

C23H14Cl2F4N4O3

541.28

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(C(F)(F)F)C=CC=N4)C3=O)=C(F)C=C2

-20°C

Ice Packs

Small Compound