HSD17B13-IN-82 - CAS 2770247-47-5

HSD17B13-IN-82 (Compound 156) serves as a potent inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 of ≤ 0.1 μM against estradiol. This compound is useful in studying various liver and metabolic disorders, including NAFLD, NASH, and drug-induced liver injury (DILI), as well as cardiovascular diseases [1].

Dehydrogenase

Metabolism

2770247-47-5

C24H15Cl3F3N3O3

556.75

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(C(F)(F)F)C=CC=C4)C3=O)=C(Cl)C=C2

-20°C

Ice Packs

Small Compound