HSD17B13-IN-86 - CAS 2770247-78-2

Compound 188 (HSD17B13-IN-86) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating potency with an IC50 value of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various conditions including liver, metabolic, and cardiovascular diseases, specifically NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2770247-78-2

C20H15Cl2N5O3S

476.34

C(NC(=O)C1=C(NC(=O)C2=CC(Cl)=C(O)C(Cl)=C2)SC=N1)C=3C=4C(N(C)N3)=CC=CC4

-20°C

Ice Packs

Small Compound