HSD17B13-IN-99 - CAS 2849338-46-9

HSD17B13-IN-99 (Compound 6) serves as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of <0.1 μM for estradiol. This compound is utilized in the study of liver, metabolic, and cardiovascular diseases, including NAFLD, NASH, and drug-induced liver injury (DILI) [1].

Dehydrogenase

Metabolism

2849338-46-9

C24H19F3N4O4

484.43

N(C(=O)C=1N=C(C(F)(F)F)C(O)=CC1)C2=C3C(N=CN(CCC4=C(OC)C=CC=C4)C3=O)=CC=C2

-20°C

Ice Packs

Small Compound