HTRA1-IN-1 - CAS 3052552-04-9

HTRA1-IN-1 (Compound 17) is a selective inhibitor of the serine protease high temperature requirement A serine peptidase 1 (HTRA1), with an IC50 of 13 nM. It shows potential for improving conditions related to HTRA1, such as age-related macular degeneration (AMD), osteoarthritis, and rheumatoid arthritis.

Serine Protease

Proteases/Proteasome

3052552-04-9

C31H43BClN3O5

583.95

[C@H](CC1=CC(Cl)=CC=C1)(C(N[C@H](C(N[C@H](B(O)O)C2CCC2)=O)CC(C)C)=O)NC(C(CC3=CC=CC=C3)(C)C)=O

-20°C

Ice Packs

Small Compound