Hu7691 free base - CAS 2241232-43-7

Hu7691 free base is an orally active, potent, and selective Akt inhibitor with anti-proliferative and neurogenic effects on various neuroblastoma cell lines. It inhibits Akt1, Akt2, and Akt3, and induces differentiation of neuroblastoma cells.

PKA, SGK, PKC, ROCK, Akt, S6 Kinase

Stem Cells, Cytoskeletal Signaling, MAPK, Cell Cycle/Checkpoint, Metabolism, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling

2241232-43-7

0.9889

C22H21F3N4O

414.423

N(C(=O)C1=C(F)C=C(C=C1)C2=CC=NN2C)[C@H]3[C@@H](CCNC3)C4=CC(F)=C(F)C=C4

-20°C

Ice Packs

Small Compound