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Human PD-L1 inhibitor I - CAS 2135542-86-6
Human PD-L1 inhibitor I - CAS 2135542-86-6
SKU:MF-0006030-01
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Product Details
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Bioactivity
Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1, exhibiting a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 inhibitor I disrupts their binding, thereby attenuating their respective functions.
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Target
PD-1/PD-L1
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Related Pathways
Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint
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CAS Number
2135542-86-6
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Molecular Formula
C110H152N26O32
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Molecular Weight
2350.576
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SMILES
CC(C)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)Cc1ccccc1)C(O)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide