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HURAT1 inhibitor 2 - CAS 1402818-99-8
HURAT1 inhibitor 2 - CAS 1402818-99-8
SKU:MF-0114579-01
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Product Details
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Bioactivity
HURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. It also exhibits some inhibitory activity against OATP1B1, with an IC50 of 0.73 μM. hURAT1 inhibitor 2 can be used in research related to hyperuricemia, gout, and other diseases associated with abnormal uric acid metabolism.
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Target
OAT
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
1402711
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Molecular Formula
C17H11Br2FO3
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Molecular Weight
442.074
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SMILES
O=C(C1=CC(Br)=C(O)C(Br)=C1)C=2C=3C=CC(F)=CC3OC2CC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound