HYDAMTIQ - CAS 1201832-32-7

HYDAMTIQ, a PARP-1/2 inhibitor (IC 50 : 29-38 nM), exhibits a range of pharmacological effects including anticancer, anti-inflammatory, and ischemic protective properties. It effectively reduces pulmonary PARP activity and alleviates symptoms such as allergen-induced cough and dyspnea while also diminishing bronchial hyperresponsiveness to methacholine. Moreover, HYDAMTIQ shows potent tumor suppressor activity in various cancers such as ovarian, breast, prostate, pancreatic, and glioblastoma multiforme. Demonstrating in vivo efficacy, HYDAMTIQ has been tested in animal models for conditions like cerebral ischemia, asthma, and cancer [1].

PARP

DNA Damage/DNA Repair, Chromatin/Epigenetic

1201832-32-7

C14H14N2O2S

274.34

OC1=C2C3=C(SC(CN(C)C)=C3)NC(=O)C2=CC=C1

-20°C

Ice Packs

Small Compound