Hydroxymethyl dasatinib - CAS 910297-58-4

Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib, demonstrates potent activity with an IC50 value of 46.7 nM in K562 CML cells [1].

Apoptosis, Drug Metabolite, Bcr-Abl, Src

Angiogenesis, Apoptosis, Metabolism, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

910297-58-4

C22H26ClN7O3S

504.01

N(C1=CC(N2CCN(CCO)CC2)=NC(C)=N1)C=3SC(C(NC4=C(CO)C=CC=C4Cl)=O)=CN3

-20°C

Ice Packs

Small Compound