HZS60 - CAS 3027529-88-7

HZS60 is a brain-penetrant NMDAR/TRPM4 inhibitor that shows promise in ameliorating cerebral ischemia. It provides significant neuroprotection against ischemic injury in primary neurons caused by NMDA and oxygen-glucose deprivation/reoxygenation. HZS60 demonstrates favorable pharmacokinetic properties and can inhibit cerebral ischemia-reperfusion injury, positioning it as a potential inhibitor for ischemic stroke.

TRP/TRPV Channel

Membrane transporter/Ion channel

3027434

C13H17F2N3

253.291

N#CC1=CC=C(F)C(=C1F)C(N(CC)CCN)C

-20°C

Ice Packs

Small Compound