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I-138 - CAS 2098211-50-6
I-138 - CAS 2098211-50-6
SKU:MF-0095347-01
Regular price
$215.85 USD
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$215.85 USD
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Product Details
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Bioactivity
I-138 is an orally active and potent reversible inhibitor of USP1-UAF1.I-138 induces mono-ubiquitination of FANCD2 and PCNA and inhibits USP1 auto-cleavage in cells.
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Target
DUB
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Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Ubiquitination
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CAS Number
2098155
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Purity
0.9941
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Molecular Formula
C26H23F3N6O
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Molecular Weight
492.5
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SMILES
C(N1C=2C(NC1=O)=CN=C(N2)C3=C(C(C)C)C=CC=C3)C4=CC=C(C=C4)C5=NC(C(F)(F)F)=CN5C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound