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I-OMe-Tyrphostin AG 538 - CAS 1094048-77-7

I-OMe-Tyrphostin AG 538 - CAS 1094048-77-7

MF-0015578-01

$48.12 USD
$48.12 USD
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Product Details

  • Bioactivity

    I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 μM) .I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-deficient PANC1 cells.

  • Target

    IGF-1R, PI3K

  • Related Pathways

    PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors

  • CAS Number

    1093964

  • Purity

    0.988

  • Molecular Formula

    C17H12INO5

  • Molecular Weight

    437.19

  • SMILES

    COc1cc(\C=C(/C#N)C(=O)c2ccc(O)c(O)c2)cc(I)c1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound