IACS-8779 disodium - CAS 2243079-27-6

IACS-8779 disodium, a highly potent STING (stimulator of interferon genes) agonist, demonstrates robust activation of the STING pathway in vitro, along with superior systemic antitumor efficacy. This compound shows a significant anti-tumor response in the B16 murine melanoma model, indicating its potential for effective cancer therapy.

Others, STING

Others, Immunology/Inflammation

2243046

C21H23N9Na2O10P2S2

733.52

OC1[C@]2([H])[C@H](N3C4=NC=NC(N)=C4N=C3)O[C@]1([H])COP([S-])(O[C@]5([H])[C@@](O[C@@H](N6C7=NC=NC(N)=C7C=C6)[C@@H]5O)([H])COP([S-])(O2)=O)=O.[Na+].[Na+]

-20°C

Ice Packs

Small Compound