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IBFAR2 - CAS 353484-02-3
IBFAR2 - CAS 353484-02-3
SKU:MF-0113052-01
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Product Details
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Bioactivity
IBFAR2, an inhibitor of BFAR, restores the CD8+ tumor-resident memory T cell subset against solid tumors. It promotes the binding of JAK2-STAT1 and enhances the phosphorylation of STAT1.
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Target
JAK, STAT
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Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Chromatin/Epigenetic, Stem Cells
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CAS Number
353484-02-3
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Molecular Formula
C19H15F3N2O2
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Molecular Weight
360.33
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SMILES
FC(F)(F)C1=C(C(C2C=CCC23)=CC=C1)NC3C4=CC=C([N+]([O-])=O)C=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound