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Molfinity

IC 86621 - CAS 404009-40-1

IC 86621 - CAS 404009-40-1

MF-0016213-01

$33.92 USD
$33.92 USD
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Product Details

  • Bioactivity

    IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break (DSB) -induced antitumor activity with an EC50 of 68 μM for DNA-PK mediated cellular DSB repair.

  • Target

    DNA-PK, Apoptosis

  • Related Pathways

    Apoptosis, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling

  • CAS Number

    403968

  • Purity

    0.9968

  • Molecular Formula

    C12H15NO3

  • Molecular Weight

    221.25

  • SMILES

    CC(=O)c1ccc(cc1O)N1CCOCC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound