ICA-105574 - CAS 316146-57-3

ICA-105574 (ICA) is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel.

Potassium Channel

Membrane transporter/Ion channel

316086

0.9977

C19H14N2O4

334.33

C(NC1=CC=C(OC2=CC=CC=C2)C=C1)(=O)C3=CC(N(=O)=O)=CC=C3

-20°C

Ice Packs

Small Compound