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Icerguastat Carbonate - CAS 1883549-35-6
Icerguastat Carbonate - CAS 1883549-35-6
SKU:MF-0116215-01
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Product Details
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Bioactivity
Icerguastat (Sephin1) Carbonate, a Guanabenz derivative lacking α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A) . It inhibits the dephosphorylation of eIF2α, thereby prolonging the protective response. Additionally, Icerguastat Carbonate exhibits antiprion activity.
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Target
Phosphatase
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Related Pathways
Metabolism
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CAS Number
1883508
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Molecular Formula
C9H11ClN4O3
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Molecular Weight
258.66
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SMILES
O=C(O)O.ClC=1C=CC=CC1C=NNC(=N)N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound