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Molfinity

ICG-001 - CAS 780757-88-2

ICG-001 - CAS 780757-88-2

SKU:MF-0015939-01

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  • Bioactivity

    ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction without interfering with β-catenin/p300 interaction. It specifically binds to CREB protein with an IC50 of 3 μM.

  • Target

    Epigenetic Reader Domain, Apoptosis, Wnt/beta-catenin

  • Related Pathways

    Cytoskeletal Signaling, Chromatin/Epigenetic, Stem Cells, Apoptosis

  • CAS Number

    780667

  • Purity

    >99.99%

  • Molecular Formula

    C33H32N4O4

  • Molecular Weight

    548.63

  • SMILES

    Oc1ccc(C[C@@H]2N3[C@H](CN(Cc4cccc5ccccc45)C2=O)N(CCC3=O)C(=O)NCc2ccccc2)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound