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ICG-001 - CAS 780757-88-2
ICG-001 - CAS 780757-88-2
SKU:MF-0015939-01
Regular price
$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction without interfering with β-catenin/p300 interaction. It specifically binds to CREB protein with an IC50 of 3 μM.
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Target
Epigenetic Reader Domain, Apoptosis, Wnt/beta-catenin
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Related Pathways
Cytoskeletal Signaling, Chromatin/Epigenetic, Stem Cells, Apoptosis
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CAS Number
780667
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Purity
>99.99%
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Molecular Formula
C33H32N4O4
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Molecular Weight
548.63
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SMILES
Oc1ccc(C[C@@H]2N3[C@H](CN(Cc4cccc5ccccc45)C2=O)N(CCC3=O)C(=O)NCc2ccccc2)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound