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ICMT-IN-1 - CAS 1313603-22-3
ICMT-IN-1 - CAS 1313603-22-3
SKU:MF-0159350-01
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Product Details
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Bioactivity
ICMT-IN-1 (compound 75) is a potent ICMT inhibitor with an IC50 of 0.0013 μM; it promotes dose-dependent cytoplasmic accumulation of ICMT in HCT-116 cells and effectively inhibits the proliferation of various cancer cell lines expressing K-Ras and N-Ras [1].
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Target
Transferase, Others
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Related Pathways
Others, Metabolism
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CAS Number
1313603-22-3
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Molecular Formula
C24H33NO2
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Molecular Weight
367.52
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SMILES
O(C1=CC=CC(=C1)NCCC2(C=3C=CC=CC3)CC(OC(C)(C)C2)(C)C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound