ICMT-IN-54 - CAS 908856-14-4

ICMT-IN-54 (compound 7c), an adamantyl analogue, serves as an ICMT inhibitor with an IC50 value of 12.4 μM, targeting the methylation process facilitated by ICMT. It specifically inhibits the methylation of BFC (N-biotinyl- (6-aminohexanoic) -S-farnesyl-L-cysteine) in Saccharomyces cerevisiae expressing ICMT, marking an indirect inhibition of ICMT-mediated methylation [1].

Others, Transferase

Metabolism, Others

908856-14-4

C29H45NO3S

487.74

C(N[C@@H](CSC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)C(O)=O)(=O)C12CC3CC(C1)CC(C2)C3

-20°C

Ice Packs

Small Compound