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Idarubicin - CAS 58957-92-9
Idarubicin - CAS 58957-92-9
SKU:MF-0039242-01
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Product Details
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Bioactivity
Idarubicin, a potent anthracycline antileukemic agent, is orally active in its application. It functions by inhibiting topoisomerase II, thus interfering with DNA replication and RNA transcription. Furthermore, Idarubicin induces DNA damage, inhibits DNA synthesis, and suppresses c-myc expression. It also demonstrates inhibitory effects on the growth of bacteria and yeasts [1] [2] [3] [4] [5].
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Target
Others, DNA/RNA Synthesis, Antifungal, Autophagy, c-Myc, Antibiotic, Antibacterial, Topoisomerase
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Related Pathways
Others, DNA Damage/DNA Repair, Autophagy, Microbiology/Virology, Cell Cycle/Checkpoint
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CAS Number
58856
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Molecular Formula
C26H27NO9
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Molecular Weight
497.49
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SMILES
O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4)C[C@](C(C)=O)(O)C1)[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound