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Idarubicin - CAS 58957-92-9

Idarubicin - CAS 58957-92-9

SKU:MF-0039242-01

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  • Bioactivity

    Idarubicin, a potent anthracycline antileukemic agent, is orally active in its application. It functions by inhibiting topoisomerase II, thus interfering with DNA replication and RNA transcription. Furthermore, Idarubicin induces DNA damage, inhibits DNA synthesis, and suppresses c-myc expression. It also demonstrates inhibitory effects on the growth of bacteria and yeasts [1] [2] [3] [4] [5].

  • Target

    Others, DNA/RNA Synthesis, Antifungal, Autophagy, c-Myc, Antibiotic, Antibacterial, Topoisomerase

  • Related Pathways

    Others, DNA Damage/DNA Repair, Autophagy, Microbiology/Virology, Cell Cycle/Checkpoint

  • CAS Number

    58856

  • Molecular Formula

    C26H27NO9

  • Molecular Weight

    497.49

  • SMILES

    O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4)C[C@](C(C)=O)(O)C1)[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound