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IDH1 Inhibitor 1 - CAS 2234285-81-3

IDH1 Inhibitor 1 - CAS 2234285-81-3

SKU:MF-0022577-01

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  • Bioactivity

    IDH1 Inhibitor 1 is an orally bioavailable, brain-penetrant, and selective mutant IDH1 inhibitor (IC50s: 0.021 μM, 0.045 μM, and 2.52 μM for IDH1R132H, IDH1R132C, and IDH1WT) .

  • Target

    Others, Isocitrate Dehydrogenase (IDH)

  • Related Pathways

    Metabolism, Others

  • CAS Number

    2234201

  • Molecular Formula

    C20H18F4N6O2

  • Molecular Weight

    450.39

  • SMILES

    C[C@H](Nc1nccc(n1)N1[C@@H](CF)COC1=O)c1cn(cn1)-c1ccc(cc1)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound