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IDH1 Inhibitor 1 - CAS 2234285-81-3
IDH1 Inhibitor 1 - CAS 2234285-81-3
SKU:MF-0022577-01
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$1,778.67 USD
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$1,778.67 USD
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Product Details
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Bioactivity
IDH1 Inhibitor 1 is an orally bioavailable, brain-penetrant, and selective mutant IDH1 inhibitor (IC50s: 0.021 μM, 0.045 μM, and 2.52 μM for IDH1R132H, IDH1R132C, and IDH1WT) .
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Target
Others, Isocitrate Dehydrogenase (IDH)
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Related Pathways
Metabolism, Others
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CAS Number
2234201
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Molecular Formula
C20H18F4N6O2
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Molecular Weight
450.39
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SMILES
C[C@H](Nc1nccc(n1)N1[C@@H](CF)COC1=O)c1cn(cn1)-c1ccc(cc1)C(F)(F)F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound