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Molfinity

IDH889 - CAS 1429179-07-6

IDH889 - CAS 1429179-07-6

SKU:MF-0033037-01

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  • Bioactivity

    IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μM, and 1.38 μM for IDH1R132H, IDH1R132C, and IDH1wt) .

  • Target

    Isocitrate Dehydrogenase (IDH), Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    1429179-07-6

  • Purity

    ≥98%

  • Molecular Formula

    C23H25FN6O2

  • Molecular Weight

    436.48

  • SMILES

    CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ncc(cn2)-c2ccc(F)c(C)c2)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound