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IDH889 - CAS 1429179-07-6
IDH889 - CAS 1429179-07-6
SKU:MF-0033037-01
Regular price
$110.31 USD
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$110.31 USD
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Product Details
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Bioactivity
IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μM, and 1.38 μM for IDH1R132H, IDH1R132C, and IDH1wt) .
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Target
Isocitrate Dehydrogenase (IDH), Dehydrogenase
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Related Pathways
Metabolism
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CAS Number
1429179-07-6
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Purity
≥98%
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Molecular Formula
C23H25FN6O2
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Molecular Weight
436.48
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SMILES
CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ncc(cn2)-c2ccc(F)c(C)c2)n1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound