IDO1/TDO-IN-1 - CAS 2379527-72-5

IDO1/TDO-IN-1 (30) is a highly effective inhibitor of IDO1 and TDO enzymes, acting through uncompetitive (Ki = 0.23 μM) and competitive (Ki = 0.73 μM) mechanisms, respectively. This compound exhibits significant capacity to induce cell apoptosis via the potential mitochondria-mediated Bcl-2/Bax pathway [1].

Others, IDO, Apoptosis, Indoleamine 2,3-Dioxygenase (IDO), Bcl-2 Family

Metabolism, Apoptosis, Others

2379450

C21H16O6

364.35

O=C1C=2C(C3=C(C1=O)C(COC(C)=O)=CO3)=CC=C4C2C=CC(=O)C4(C)C

-20°C

Ice Packs

Small Compound