IDOR-1117-2520 - CAS 2737274-49-4

IDOR-1117-2520 is a highly potent and selective antagonist of CCR6, effectively impeding CCL20-mediated calcium flow with an IC50 of 63 nM and inhibiting β-arrestin recruitment to human CCR6 with an IC50 of 30 nM in cells expressing recombinant human CCR6. This compound is suitable for researching autoimmune diseases [1].

CCR

Immunology/Inflammation, GPCR/G Protein, Microbiology/Virology

2737274-49-4

C25H32N4O3

436.55

[C@](O)([C@]1(C)CN(C)C1)(C=2C=C(C=NC2)C=3N=C(C(C)(C)O)ON3)C4=CC=C(C(C)C)C=C4

-20°C

Ice Packs

Small Compound