Molfinity
IDR 1002 - CAS 1224095-25-3
IDR 1002 - CAS 1224095-25-3
SKU:MF-0100322
Couldn't load pickup availability
Share

Product Details
-
Bioactivity
IDR 1002, an innate defense regulator peptide, effectively diminishes bacterial load and mitigates inflammatory responses in murine models of sinusitis and acute bacterial lung infections. It suppresses LPS-induced activation of NF-κB and COX-2 while promoting the phosphorylation and activation of p38, ERK1/2, MSK1, and CREB.
-
Target
Integrin
-
Related Pathways
Cytoskeletal Signaling
-
CAS Number
1224095-25-3
-
Molecular Formula
C79H130N26O13
-
Molecular Weight
1652.06
-
SMILES
O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
-
Storage Temperature
-20°C
-
Shipping Conditions
Ice Packs
-
Category
Peptide