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Molfinity

IDR 1002 - CAS 1224095-25-3

IDR 1002 - CAS 1224095-25-3

SKU:MF-0100322

Regular price $429.08 USD
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  • Bioactivity

    IDR 1002, an innate defense regulator peptide, effectively diminishes bacterial load and mitigates inflammatory responses in murine models of sinusitis and acute bacterial lung infections. It suppresses LPS-induced activation of NF-κB and COX-2 while promoting the phosphorylation and activation of p38, ERK1/2, MSK1, and CREB.

  • Target

    Integrin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    1224095-25-3

  • Molecular Formula

    C79H130N26O13

  • Molecular Weight

    1652.06

  • SMILES

    O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide