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Ifebemtinib tosylate - CAS 2761021-80-9
Ifebemtinib tosylate - CAS 2761021-80-9
SKU:MF-0118899-01
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Product Details
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Bioactivity
Ifebemtinib (tosylate) (BI-853520 (tosylate) ; IN-10018 (tosylate) ) is a highly selective PTK2 kinase inhibitor with anti-tumor properties. It inhibits FAK autophosphorylation in prostate cancer cells and suppresses spheroid formation and in situ tumor growth in vivo. Ifebemtinib (tosylate) is applicable in cancer research, including studies on solid tumors, breast cancer, and malignant pleural mesothelioma.
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Target
FAK
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Related Pathways
Cytoskeletal Signaling, Angiogenesis, Tyrosine Kinase/Adaptors
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CAS Number
2760932
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Molecular Formula
C35H36F4N6O7S
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Molecular Weight
760.76
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SMILES
O=C(NC1CCN(C)CC1)C=2C=C(OC)C(=CC2F)NC3=NC=C(C(=N3)OC4=CC=CC5=C4C(=O)N(C)C5)C(F)(F)F.O=S(=O)(O)C1=CC=C(C=C1)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound