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Ifebemtinib tosylate - CAS 2761021-80-9

Ifebemtinib tosylate - CAS 2761021-80-9

SKU:MF-0118899-01

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  • Bioactivity

    Ifebemtinib (tosylate) (BI-853520 (tosylate) ; IN-10018 (tosylate) ) is a highly selective PTK2 kinase inhibitor with anti-tumor properties. It inhibits FAK autophosphorylation in prostate cancer cells and suppresses spheroid formation and in situ tumor growth in vivo. Ifebemtinib (tosylate) is applicable in cancer research, including studies on solid tumors, breast cancer, and malignant pleural mesothelioma.

  • Target

    FAK

  • Related Pathways

    Cytoskeletal Signaling, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    2760932

  • Molecular Formula

    C35H36F4N6O7S

  • Molecular Weight

    760.76

  • SMILES

    O=C(NC1CCN(C)CC1)C=2C=C(OC)C(=CC2F)NC3=NC=C(C(=N3)OC4=CC=CC5=C4C(=O)N(C)C5)C(F)(F)F.O=S(=O)(O)C1=CC=C(C=C1)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound