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IFSP1 - CAS 150651-39-1
IFSP1 - CAS 150651-39-1
SKU:MF-0022594-01
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$31.68 USD
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$31.68 USD
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Product Details
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Bioactivity
IFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R) -RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1.
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Target
Ferroptosis
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Related Pathways
Apoptosis
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CAS Number
150611
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Purity
0.9974
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Molecular Formula
C20H13N5
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Molecular Weight
323.35
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SMILES
Cc1ccc(cc1)-c1c(C#N)c(N)n2c3ccccc3nc2c1C#N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound