II-B08 - CAS 1143579-78-5

II-B08 is a cell-permeable SHP2 inhibitor (IC50 = 5.5 μM) . II-B08 blocks growth factor stimulated ERK1/2 activation and hematopoietic progenitor proliferation.

Others, Phosphatase

Metabolism, Others

1143496

C33H27N5O4

557.6

CN1C(=C(C=2C1=CC(O)=C(C(O)=O)C2)C3=CN(CCC(NC4=CC=C(C=C4)C5=CC=CC=C5)=O)N=N3)C6=CC=CC=C6

-20°C

Ice Packs

Small Compound