III-31-C - CAS 398515-96-3

III-31-C is a (hydroxyethyl) urea γ-secretase inhibitor. It reduces the production of Aऔ, with an IC50 of 10 nM in cell-free γ-secretase assays and 200 nM in APP-transfected cells. III-31-C is applicable for Alzheimer's disease research.

Gamma-secretase

Proteases/Proteasome, Stem Cells, Neuroscience

398416

C35H52N4O7

640.81

N(CC1=CC=CC=C1)(C[C@H]([C@H](CC2=CC=CC=C2)NC(OC(C)(C)C)=O)O)C(N[C@H](C(N[C@H](C(OC)=O)[C@@H](C)C)=O)CC(C)C)=O

-20°C

Ice Packs

Small Compound